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Image Search Results
Journal: Journal of advanced research
Article Title: Short-chain fatty acid butyrate against TMAO activating endoplasmic-reticulum stress and PERK/IRE1-axis with reducing atrial arrhythmia.
doi: 10.1016/j.jare.2024.08.009
Figure Lengend Snippet: Fig. 4. SB supplement ameliorated TMAO-mediated activation of ER stress signaling and dysregulation of ionic signaling. (A) and (B) Representative images and statistical data show the expression of pPERK, PERK, pIRE1a, IRE1a, pNF-jB, NF-jB, pIP3R, IP3R, NCX, Kv1.5, and b-actin in HL-1 cells from control group (n = 3), TMAO treated (n = 3), SB treated (n = 3), and TMAO combined with SB treated group (n = 3) in three independent experiments. b-Actin was used as a loading control. *P < 0.05. **P < 0.01. TMAO versus control or SB or TMAO combined with SB treatment.
Article Snippet: Then, the blots were incubated with primary
Techniques: Activation Assay, Expressing, Control
Journal: Journal of advanced research
Article Title: Short-chain fatty acid butyrate against TMAO activating endoplasmic-reticulum stress and PERK/IRE1-axis with reducing atrial arrhythmia.
doi: 10.1016/j.jare.2024.08.009
Figure Lengend Snippet: Fig. 8. SB supplement ameliorated atrial fibrosis and PERK/IRE1a/NF-jB axis of TMAO-treated mice. The expression of atrial fibrosis (blue area) was detected by Masson’s staining and immunostaining of pPERK, pIRE1a, and pNF-jB in the atrium tissues derived from mice gavage with control (n = 5), TMAO (n = 5), and TMAO combined with SB (n = 5). The expressions of pPERK are indicated by hollow arrowheads. (bar, 25 lm). ** p < 0.01. TMAO treatment versus control group or TMAO combined with SB treated group. (For interpretation of the references to colour in this Fig. legend, the reader is referred to the web version of this article.)
Article Snippet: Then, the blots were incubated with primary
Techniques: Expressing, Staining, Immunostaining, Derivative Assay, Control